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神经肽在进食行为调节中的作用:胆囊收缩素、蛙皮素、神经肽Y和甘丙肽的综述

Role of neuropeptides in the regulation of feeding behavior: a review of cholecystokinin, bombesin, neuropeptide Y, and galanin.

作者信息

Lee M C, Schiffman S S, Pappas T N

机构信息

Department of Surgery, Duke University Medical Center, Durham, NC 27710.

出版信息

Neurosci Biobehav Rev. 1994 Fall;18(3):313-23. doi: 10.1016/0149-7634(94)90045-0.

DOI:10.1016/0149-7634(94)90045-0
PMID:7527134
Abstract

The purpose of this report is to provide a review of four peptides (cholecystokinin, bombesin, neuropeptide Y, galanin) and their role in feeding behavior. Cholecystokinin (CCK) and bombesin (BBS) are considered satiety peptides, and neuropeptide Y (NPY) and galanin (GAL) have been proposed as appetite peptides. For the purposes of this review, satiety refers to the physiological cessation of feeding, and appetite refers to the drive to eat and exists in gradations.

摘要

本报告旨在综述四种肽(胆囊收缩素、蛙皮素、神经肽Y、甘丙肽)及其在摄食行为中的作用。胆囊收缩素(CCK)和蛙皮素(BBS)被认为是饱腹感肽,而神经肽Y(NPY)和甘丙肽(GAL)则被认为是食欲肽。在本综述中,饱腹感是指摄食的生理停止,而食欲是指进食的驱动力,且存在不同程度。

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