Zatloukal P, Glagolicová A, Mĕricka O, Bezdícek P
I. klinika tuberkulózy a respiracních nemocí, 1. lékarské fakulty Univerzity Karlovy, Praha.
Sb Lek. 1993;94(4):327-31.
Using radioimmunoassay method the alpha-subunit of human chorionic gonadotropin (alpha-HCG) serum levels were measured in 112 bronchogenic carcinoma patients and in 48 patients with various non-cancerous lung diseases. The aim of this study was to assess the utility of alpha-HCG as a tumor marker for differential diagnosis of lung cancer. The incidence of elevated alpha-HCG serum level bronchogenic carcinoma group was 4.4%, in non-cancerous diseases group it was 4.1%, respectively. The difference between these two groups wasn't statistically significant. The elevation of the alpha-HCG was unrelated to the histologic type of lung cancer. The finding suggest that alpha-HCG serum level can't help in discriminating between patients with bronchogenic carcinoma and those with non-cancerous lung diseases.
采用放射免疫分析法测定了112例支气管肺癌患者和48例各种非癌性肺部疾病患者血清中人绒毛膜促性腺激素α亚基（α-HCG）水平。本研究的目的是评估α-HCG作为肺癌鉴别诊断肿瘤标志物的效用。支气管肺癌组血清α-HCG水平升高的发生率为4.4%，非癌性疾病组为4.1%。两组之间的差异无统计学意义。α-HCG升高与肺癌的组织学类型无关。研究结果表明，血清α-HCG水平无助于区分支气管肺癌患者和非癌性肺部疾病患者。
