Peracchia A, Bonavina L, Pavanello M, Montorsi M, Ruol A, Segalin A
Istituto di Chirurgia Generale e Oncologia Chirurgica, Università di Milano.
Chir Ital. 1994;46(3):1-4.
Between 1980 and 1993, out of 635 patients presenting with an adenocarcinoma of the esophagogastric junction, 74 (11.7%) had a neoplasm arising from a columnar specialized epithelium lining the distal esophagus. Fifty of these patients (68%) underwent a curative (R0) resection. 36 patients (72%) were in stage 0, I or II, and the 5-year actuarial survival rate was 44%. The survival rate dropped to 13% when nodal metastases were present. We conclude that the long-lasting symptoms during the pre-neoplastic phase, and a closer endoscopic surveillance allow a early diagnosis of Barrett adenocarcinoma. Surgical therapy must be radical in these patients in order to improve prognosis.
1980年至1993年间，在635例食管胃交界腺癌患者中，74例（11.7%）肿瘤起源于食管远端柱状特化上皮。其中50例患者（68%）接受了根治性（R0）切除。36例患者（72%）处于0期、I期或II期，5年精算生存率为44%。出现淋巴结转移时，生存率降至13%。我们得出结论，肿瘤前期的长期症状以及更密切的内镜监测可实现巴雷特腺癌的早期诊断。为改善预后，这些患者必须接受根治性手术治疗。
