Drouet M, Gros N, Sabbah A
Laboratoire d'Immuno-Allergologie- CHU, Angers.
Allerg Immunol (Paris). 1994 Oct;26(8):289-92, 295-6.
Through the multidetection test for specific IgE to pneumoallergens (Aero-Matrix Plus, Abbott) our attention has been drawn to polysensitization to pollens. Amongst these pollen tests, plantain seems to be frequently associated with sensitization to latex. The aim of this work at first, is therefore to verify the reality of the frequency of the association between latex and plantain sensitization. However, the conclusions are difficult, since there are no patients who are only sensitive to plantain as sensitivity to this allergen is always found in a pollen polysensitization. at least associated with grass pollens; at most associated with a number of other pollens. The double profile (perhaps plantain + / grass pollen +, or perhaps plantain + / grass pollen + / other pollens +) is determinant in prediction of sensitivity to latex, which is found essentially in the group plantain + / grass pollen + / other pollens +. This study has also shown that amongst the population who have specific IgE to latex (IgEs) (sensitized or allergic): the patients who have a clinical history of allergy to latex have no profile of pollen polysensitization; the non-allergic but sensitive patients (IgE positive, but no clinical signs on contact with latex) show an extreme pollen polysensitization. This poses a problem of different antigenic determinants or perhaps two different pathways to sensitization to latex.
通过针对气传变应原的特异性IgE多检测试验（Aero-Matrix Plus，雅培公司），我们的注意力被吸引到对花粉的多重致敏现象上。在这些花粉检测中，车前草似乎经常与对乳胶的致敏相关。因此，这项工作的首要目的是验证乳胶致敏与车前草致敏之间关联频率的实际情况。然而，得出结论很困难，因为不存在仅对车前草敏感的患者，因为对这种变应原的敏感性总是在花粉多重致敏中被发现，至少与草花粉相关，至多与多种其他花粉相关。双重特征（可能是车前草+/草花粉+，或者可能是车前草+/草花粉+/其他花粉+）在预测对乳胶的敏感性方面起决定性作用，这种敏感性主要在车前草+/草花粉+/其他花粉+组中被发现。这项研究还表明，在对乳胶有特异性IgE（IgEs）（致敏或过敏）的人群中：有乳胶过敏临床病史的患者没有花粉多重致敏特征；非过敏但敏感的患者（IgE阳性，但接触乳胶时无临床症状）表现出极端的花粉多重致敏。这就产生了不同抗原决定簇的问题，或者可能是两种不同的乳胶致敏途径。
