Chernokhvostova E V, Kotova T S, German G P, Atovmian O I
Ter Arkh. 1990;62(11):111-4.
Total IgE, IgE and IgG4 antibodies to offending allergens were studied in 118 hay fever patients with allergy to tree pollen or to grass pollen. No difference in the level of total IgE and IgE antibodies was found between these groups of patients while the IgG4 antibody level was significantly higher in tree pollen-allergic patients. It has been established that in tree pollen allergy, the determination of IgG4 antibodies is of no less diagnostic value than the assay of IgE antibodies. The authors discuss the problems of the prognostic value of IgG4 antibody increase during the hyposensitization therapy and of a possible relationship between IgG4 antibodies and allergy to vegetable food often associated with tree pollen allergy.
对118名对树花粉或草花粉过敏的花粉症患者进行了针对致敏变应原的总IgE、IgE和IgG4抗体研究。在这些患者组之间，总IgE和IgE抗体水平未发现差异，而树花粉过敏患者的IgG4抗体水平显著更高。已经确定，在树花粉过敏中，IgG4抗体的测定与IgE抗体检测具有同样的诊断价值。作者讨论了在减敏治疗期间IgG4抗体增加的预后价值问题，以及IgG4抗体与常与树花粉过敏相关的植物性食物过敏之间可能存在的关系。
