Sun H Y, Li Z X, Liu W L, Xu H Z, Yang S H, Tang J Z, Hao L J
Abteilung für Klinische Immunologie, Tongji Klinik, Tongji Medizinische Universität, Wuhan.
J Tongji Med Univ. 1994;14(3):178-80. doi: 10.1007/BF02886802.
28 cases of hemophilia were examined for HCV infection status by using the Kehua anti-HCV ELISA kit of second generation. It was found that the infection rate was 78.5% and the infection rate was even higher with patients who had received transfusions or preparations of coagulatory factors. 10 families of 15 patients were also investigated. It was found that of 15 hemophilia patients, 12 showed positive anti-HCV, while none of their 53 family members exhibited any positive anti-HCV. In 8 children of 9 couples no positive anti-HCV was found. Our results revealed that the hemophilia patient may get infected with HCV by receiving multiple transfusions or preparation of coagulatory factors. The risk of getting infected with HCV via daily-life contact including sexual contact is extremely low.
采用第二代科华抗 - HCV ELISA试剂盒对28例血友病患者进行HCV感染状况检测。结果发现感染率为78.5%，接受过输血或凝血因子制剂治疗的患者感染率更高。还对15例患者的10个家庭进行了调查。结果发现，15例血友病患者中，12例抗 - HCV呈阳性，而他们的53名家庭成员中无一例抗 - HCV呈阳性。9对夫妇的8名子女中未发现抗 - HCV阳性。我们的结果显示，血友病患者可能因多次输血或接受凝血因子制剂治疗而感染HCV。通过包括性接触在内的日常生活接触感染HCV的风险极低。
