Miller E, Tookey P, Morgan-Capner P, Hesketh L, Brown D, Waight P, Vurdien J, Jones G, Peckham C
Immunisation Division, PHLS Communicable Disease Surveillance Centre.
Commun Dis Rep CDR Rev. 1994 Nov 11;4(12):R146-52.
A downward trend in the incidence of acquired rubella in England and Wales was reversed in 1993 when there were local outbreaks. These affected young adult males in particular, especially those living in college residences. Some spread to local antenatal populations occurred. Twenty-five confirmed infections were reported in pregnant women, most of whom were young and in their first pregnancy; this compares with totals of 12 and two in 1991 and 1992, respectively. Reports of congenital rubella have not risen since the 1993 outbreaks. Diagnosis lags behind birth, however, and further evaluation may be needed. Notifications of 14 infants, including one set of triplets, born with congenital infection since the beginning of 1991 have been received. Nine of the 12 mothers were immigrants, and three of these acquired their infection abroad. Data on antibody prevalence have revealed a large pool of susceptible males aged 10 to 25 years, which indicates that outbreaks in males would continue for some years if no action were taken. The national measles and rubella vaccination campaign in schools this month should abolish the difference in susceptibility between boys and girls up to 16 years of age and hasten progress towards the interruption of rubella transmission in the United Kingdom. Susceptibility in girls aged 13 to 14 years rose to 5.8% in 1993 from an average of 3.6% between 1986 and 1992. This suggests that the vaccination of schoolgirls has recently declined, but this component of the selective rubella vaccination programme will be discontinued after the measles and rubella campaign.(ABSTRACT TRUNCATED AT 250 WORDS)
1993年,英格兰和威尔士获得性风疹发病率的下降趋势出现逆转,当时出现了局部疫情。这些疫情尤其影响到年轻成年男性,特别是那些住在大学宿舍的人。疫情还出现了向当地产前人群的一定传播。报告称有25名孕妇确诊感染风疹,其中大多数年龄较小且为首次怀孕;而1991年和1992年的确诊总数分别为12例和2例。自1993年疫情爆发以来,先天性风疹的报告病例数并未增加。然而,诊断滞后于出生时间,可能需要进一步评估。自1991年初以来,已收到14例先天性感染风疹婴儿的报告,其中包括一组三胞胎。12名母亲中有9名是移民,其中3名在国外感染。抗体流行率数据显示,有大量10至25岁的易感男性,这表明如果不采取行动,男性中的疫情将持续数年。本月在学校开展的全国麻疹和风疹疫苗接种活动应消除16岁以下男孩和女孩在易感性上的差异,并加快在英国阻断风疹传播的进程。1993年,13至14岁女孩的易感性从1986年至1992年的平均3.6%升至5.8%。这表明最近在校女生的疫苗接种率有所下降,但选择性风疹疫苗接种计划的这一部分将在麻疹和风疹活动后停止。(摘要截选至250词)