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[恶性梗阻性黄疸的放射治疗]

[Radiotherapy of malignant obstructive jaundice].

作者信息

Nilles A, Frommhold H, Bruggmoser G

机构信息

Abteilung Strahlentherapie, Radiologische Universitätsklinik Freiburg.

出版信息

Chirurg. 1994 Oct;65(10):832-5.

PMID:7529669
Abstract

Brachytherapy using the afterloading technique with iridium 192 and percutaneous irradiation using 16 MV photons are used for the irradiation of malignant obstructive jaundice. Mostly, however, a combination of both methods can be used to advantage. In bile duct tumors and Klatskin tumors, the endoluminal part can be treated using brachytherapy. The extralumenal growth and, if necessary, all affected regional lymph node areas can be treated by a 3D planned, percutaneous, moving field technique. Intraoperative radiotherapy can be used in a few cases as booster irradiation of tumor conglomerates at the porta hepatis. The decision to use irradiation must be made very carefully since solid tumors are usually involved that require a high target dose, the application of which can lead to unacceptable side effects. The radio-oncological spectrum is therefore confined predominantly to palliative therapy.

摘要

使用铱192后装技术的近距离放射治疗和使用16兆伏光子的经皮照射用于恶性梗阻性黄疸的照射。然而,大多数情况下,两种方法联合使用可取得更好效果。在胆管肿瘤和肝门部胆管癌中,腔内部分可采用近距离放射治疗。腔外生长部分以及必要时所有受影响的区域淋巴结区域可通过三维计划的经皮移动野技术进行治疗。少数情况下,术中放疗可作为肝门部肿瘤团块的加强照射。由于通常涉及实体瘤,需要高靶剂量,而高靶剂量的应用可能导致不可接受的副作用,因此必须非常谨慎地做出使用放疗的决定。因此,放射肿瘤学的范围主要限于姑息治疗。

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