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[抗原性细菌多糖。洋葱伯克霍尔德菌C、I、O1和O4血清群O特异性多糖的结构]

[Antigenic bacterial polysaccharides. Structure of O-specific polysaccharides from Pseudomonas cepacia serogroups C, I, O1, and O4].

作者信息

Paramonov N A, Shashkov A S, Knirel' Iu A, Soldatkina M A, Zakharova I Ia

出版信息

Bioorg Khim. 1994 Aug-Sep;20(8-9):984-93.

PMID:7530009
Abstract

Like some Pseudomonas cepacia serogroups studied earlier, serogroups C, I (Nakamura), O1 and O4 (Heidt) are characterized by the presence of at least two structurally different O-antigenic polysaccharide chains in cell-wall lipopolysaccharides. On the basis of acid hydrolysis, methylation, 1H- and 13C-NMR spectroscopy, including computer-assisted 13C-NMR-based analysis, the complete structures of the predominant polysaccharides of serogroups I (I), C and O4 (III) and the minor polysaccharides of serogroups I (II) and O1 (V) were established, and the structure of the predominant polysaccharide of serogroup O1 (IV) established earlier (Cox A. D., Wilkinson S. G.@Carbohydr. Res. 1990. V. 195. No 2. P. 295-301) was confirmed.

摘要

与之前研究的一些洋葱伯克霍尔德菌血清群一样,血清群C、I(中村)、O1和O4(海德特)的特征是细胞壁脂多糖中存在至少两条结构不同的O抗原多糖链。基于酸水解、甲基化、1H和13C核磁共振光谱,包括基于计算机辅助13C核磁共振的分析,确定了血清群I(I)、C和O4(III)的主要多糖以及血清群I(II)和O1(V)的次要多糖的完整结构,并证实了先前确定的血清群O1(IV)主要多糖的结构(考克斯A.D.,威尔金森S.G.@碳水化合物研究.1990年.第195卷.第2期.第295 - 301页)。

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