Anand V K, Arrowood J P, Krolls S O
Department of Surgery, University of Mississippi Medical Center, Jackson 39126-4505.
Laryngoscope. 1995 Jan;105(1):14-6. doi: 10.1288/00005537-199501000-00006.
The odontogenic keratocyst (OKC) is a locally aggressive neoplasm with rates of recurrence reported as high as 60%. Correlation between histopathology and the likelihood of recurrence remains a subject of controversy. In this review of the authors' experience in treating 50 patients with OKC between 1977 and 1993, 58 specimens were studied to correlate the likelihood of recurrence with the presence of the following histologic features--parakeratosis, orthokeratosis, satellite cysts, epithelial rests, or epithelial proliferation. Orthokeratinized cysts were associated with a higher recurrence rate than in previously reported studies. Disruption of the epithelial lining in the resected specimen was found to be a primary determinant of recurrence.
牙源性角化囊肿（OKC）是一种具有局部侵袭性的肿瘤，其复发率据报道高达60%。组织病理学与复发可能性之间的相关性仍是一个有争议的话题。在本文作者对1977年至1993年间治疗的50例OKC患者的经验回顾中，研究了58个标本，以将复发可能性与以下组织学特征的存在相关联——不全角化、正角化、卫星囊肿、上皮剩余或上皮增生。与先前报道研究相比，正角化囊肿的复发率更高。发现切除标本中上皮衬里的破坏是复发的主要决定因素。
