乙醇引起的肝脏代谢性超极化：镁离子和氢离子在决定非渗透性细胞内阴离子电荷及代谢反应能量方面的重要性。 - Suppr

Metabolic hyperpolarization of liver by ethanol: the importance of Mg2+ and H+ in determining impermeant intracellular anionic charge and energy of metabolic reactions.

作者信息

Veech R L, Gates D N, Crutchfield C, Gitomer W L, Kashiwaya Y, King M T, Wondergem R

机构信息

Laboratory of Metabolism and Molecular Biology, National Institute on Alcohol Abuse and Alcoholism, Rockville MD 20852-1823.

出版信息

Alcohol Clin Exp Res. 1994 Oct;18(5):1040-56. doi: 10.1111/j.1530-0277.1994.tb00081.x.

DOI:10.1111/j.1530-0277.1994.tb00081.x

PMID:7531402

Abstract

摘要

相似文献

Metabolic hyperpolarization of liver by ethanol: the importance of Mg2+ and H+ in determining impermeant intracellular anionic charge and energy of metabolic reactions.

Alcohol Clin Exp Res. 1994 Oct;18(5):1040-56. doi: 10.1111/j.1530-0277.1994.tb00081.x.

Contribution of NMR spectroscopy to the biochemical investigation of ethanol-induced perturbations in hepatic metabolism.

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Coupling among changes in energy metabolism, acid-base homeostasis, and ion fluxes in ischemia.

Can J Physiol Pharmacol. 1992;70 Suppl:S170-5. doi: 10.1139/y92-259.

[Liver metabolism and acid-base balance].

Anasthesiol Intensivmed Notfallmed Schmerzther. 1995 Oct;30 Suppl 1:S48-51. doi: 10.1055/s-2007-996561.

Magnesium-dependent block of the light-activated and trp-dependent conductance in Drosophila photoreceptors.

J Neurophysiol. 1995 Dec;74(6):2590-9. doi: 10.1152/jn.1995.74.6.2590.

Intracellular Mg2+ may act as a co-factor in ion channel function.

Trends Neurosci. 1988 Nov;11(11):475-7. doi: 10.1016/0166-2236(88)90003-3.

Permeability and Mg2+ blockade of histamine-operated cation channel in endothelial cells of rat intrapulmonary artery.

J Physiol. 1992 May;450:395-408. doi: 10.1113/jphysiol.1992.sp019133.

Transmembrane Mg2+ currents and intracellular free Mg2+ concentration in Paramecium tetraurelia.

J Membr Biol. 1998 Jul 1;164(1):11-24. doi: 10.1007/s002329900389.

The effect of temporary hepatic ischemia on liver surface pH and potassium ion activity in the rat.

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Some processes of energy saving and expenditure occurring during ethanol perfusion in the isolated liver of fed rats; a Nuclear Magnetic Resonance study.

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Metabolic hyperpolarization of liver by ethanol: the importance of Mg2+ and H+ in determining impermeant intracellular anionic charge and energy of metabolic reactions.

作者信息

Veech R L, Gates D N, Crutchfield C, Gitomer W L, Kashiwaya Y, King M T, Wondergem R

机构信息

Laboratory of Metabolism and Molecular Biology, National Institute on Alcohol Abuse and Alcoholism, Rockville MD 20852-1823.

出版信息

Alcohol Clin Exp Res. 1994 Oct;18(5):1040-56. doi: 10.1111/j.1530-0277.1994.tb00081.x.

DOI:10.1111/j.1530-0277.1994.tb00081.x

PMID:7531402

Abstract

摘要

相似文献

Metabolic hyperpolarization of liver by ethanol: the importance of Mg2+ and H+ in determining impermeant intracellular anionic charge and energy of metabolic reactions.

Alcohol Clin Exp Res. 1994 Oct;18(5):1040-56. doi: 10.1111/j.1530-0277.1994.tb00081.x.

Contribution of NMR spectroscopy to the biochemical investigation of ethanol-induced perturbations in hepatic metabolism.

Alcohol Alcohol. 1994 Sep;29(5):523-34.

Effects of ethanol on NMDA receptors in brain: possibilities for Mg(2+)-ethanol interactions.

Alcohol Clin Exp Res. 1994 Oct;18(5):1069-75. doi: 10.1111/j.1530-0277.1994.tb00083.x.

Coupling among changes in energy metabolism, acid-base homeostasis, and ion fluxes in ischemia.

Can J Physiol Pharmacol. 1992;70 Suppl:S170-5. doi: 10.1139/y92-259.

[Liver metabolism and acid-base balance].

Anasthesiol Intensivmed Notfallmed Schmerzther. 1995 Oct;30 Suppl 1:S48-51. doi: 10.1055/s-2007-996561.

Magnesium-dependent block of the light-activated and trp-dependent conductance in Drosophila photoreceptors.

J Neurophysiol. 1995 Dec;74(6):2590-9. doi: 10.1152/jn.1995.74.6.2590.

Intracellular Mg2+ may act as a co-factor in ion channel function.

Trends Neurosci. 1988 Nov;11(11):475-7. doi: 10.1016/0166-2236(88)90003-3.

Permeability and Mg2+ blockade of histamine-operated cation channel in endothelial cells of rat intrapulmonary artery.

J Physiol. 1992 May;450:395-408. doi: 10.1113/jphysiol.1992.sp019133.

Transmembrane Mg2+ currents and intracellular free Mg2+ concentration in Paramecium tetraurelia.

J Membr Biol. 1998 Jul 1;164(1):11-24. doi: 10.1007/s002329900389.

The effect of temporary hepatic ischemia on liver surface pH and potassium ion activity in the rat.

Langenbecks Arch Chir. 1995;380(1):58-61. doi: 10.1007/BF00184417.

引用本文的文献

Aldose reductase, fructose and fat production in the liver.

Biochem J. 2025 Mar 5;482(5):295-307. doi: 10.1042/BCJ20240748.

Relationship between inorganic ion distribution, resting membrane potential, and the Δ' of ATP hydrolysis: a new paradigm.

FASEB J. 2019 Dec;33(12):13126-13130. doi: 10.1096/fj.201901942R. Epub 2019 Nov 5.

The "great" controlling nucleotide coenzymes.

IUBMB Life. 2019 May;71(5):565-579. doi: 10.1002/iub.1997. Epub 2019 Jan 9.

Microwave irradiation decreases ATP, increases free [Mg²⁺], and alters in vivo intracellular reactions in rat brain.

J Neurochem. 2012 Dec;123(5):668-75. doi: 10.1111/jnc.12026.

A ketone ester diet increases brain malonyl-CoA and Uncoupling proteins 4 and 5 while decreasing food intake in the normal Wistar Rat.

J Biol Chem. 2010 Aug 20;285(34):25950-6. doi: 10.1074/jbc.M110.138198. Epub 2010 Jun 7.

Alterations in brain glucose utilization accompanying elevations in blood ethanol and acetate concentrations in the rat.

Alcohol Clin Exp Res. 2010 Feb;34(2):375-81. doi: 10.1111/j.1530-0277.2009.01099.x. Epub 2009 Nov 24.

Some processes of energy saving and expenditure occurring during ethanol perfusion in the isolated liver of fed rats; a Nuclear Magnetic Resonance study.

BMC Physiol. 2004 Mar 1;4:3. doi: 10.1186/1472-6793-4-3.

The resting membrane potential of cells are measures of electrical work, not of ionic currents.

Integr Physiol Behav Sci. 1995 Sep-Dec;30(4):283-307. doi: 10.1007/BF02691602.

Metabolic hyperpolarization of liver by ethanol: the importance of Mg2+ and H+ in determining impermeant intracellular anionic charge and energy of metabolic reactions.

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Metabolic hyperpolarization of liver by ethanol: the importance of Mg2+ and H+ in determining impermeant intracellular anionic charge and energy of metabolic reactions.

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