Gertsch P, Yip S K, Chow L W, Lauder I J
Department of Surgery, Queen Mary Hospital, University of Hong Kong.
Arch Surg. 1995 Feb;130(2):177-81. doi: 10.1001/archsurg.1995.01430020067011.
To define by actual standards the results of treatment of free perforation of gastric carcinoma in a consecutive number of patients treated at one institution.
Case series of patients with perforated adenocarcinoma of the stomach treated in Hong Kong between 1984 and 1992.
Urban academic medical center.
Thirty-four Chinese patients who were operated on for perforated gastric carcinoma. A risk scoring system was used to predict postoperative mortality. Factors with a possible influence on postoperative mortality and long-term survival were studied using univariate and multivariate analysis.
All patients underwent laparotomy, which was performed for closure of the perforation in four patients and for gastrectomy in 30.
Thirty-day mortality and survival times.
The 30-day mortality rate was 20%, and the median survival time was 10 months (range, 2 to 92 months). The risk score was the only significant predictor of 30-day mortality, and the pathologic TNM staging, of long-term survival.
A significant proportion of patients can be saved and offered good palliation with emergency gastrectomy; those likely to die can be identified before surgery.
根据实际标准确定在同一机构连续治疗的一批胃癌游离穿孔患者的治疗结果。
1984年至1992年在香港接受治疗的胃穿孔腺癌患者的病例系列。
城市学术医疗中心。
34例接受胃癌穿孔手术的中国患者。使用风险评分系统预测术后死亡率。采用单因素和多因素分析研究可能影响术后死亡率和长期生存的因素。
所有患者均接受剖腹手术,其中4例患者进行穿孔闭合术,30例患者进行胃切除术。
30天死亡率和生存时间。
30天死亡率为20%,中位生存时间为10个月(范围为2至92个月)。风险评分是30天死亡率的唯一显著预测因素,而病理TNM分期是长期生存的显著预测因素。
相当一部分患者可通过急诊胃切除术获救并获得良好的姑息治疗;手术前可识别出可能死亡的患者。