Pyle R B, Mayer J E, Lindsay W G, Jorgensen C R, Wang Y, Nicoloff D M
Ann Thorac Surg. 1978 Oct;26(4):336-43. doi: 10.1016/s0003-4975(10)62899-8.
The central-flow low profile disc-valve prosthesis has been offered as an alternative to ball- and tissue-valve prostheses. Extensive laboratory investigation with both pulse duplicator and experimental animals has been reported for the Lillehei-Kaster prosthesis. A series of patients receiving this prosthesis underwent postoperative cardiac catheterization to better define the hemodynamic function of this prosthesis in vivo. Because of the variations in reports of hemodynamic data from various institutions, the results of post-operative studies in an earlier group of patients with Starr-Edwards prostheses were used as a standard for comparison. Good hemodynamic function was found with the pivoting-disc prosthesis in all but the smallest valve sizes. Lillehei-Kaster and early model Starr-Edwards prostheses with equivalent tissue annulus dimensions were found to have nearly equal valve areas in vivo in the aortic position. The Lillehei-Kaster mitral valves provided larger areas than Starr-Edwards prostheses in large tissue annulus sizes.
中心血流低轮廓盘形瓣膜假体已被用作球瓣和组织瓣膜假体的替代方案。对于 Lillehei-Kaster 假体,已经报道了在脉搏复制器和实验动物上进行的广泛实验室研究。一系列接受这种假体的患者术后接受了心脏导管检查,以更好地确定这种假体在体内的血流动力学功能。由于各机构血流动力学数据报告存在差异,早期一组接受 Starr-Edwards 假体患者的术后研究结果被用作比较标准。除了最小的瓣膜尺寸外,枢轴盘形假体在所有情况下都具有良好的血流动力学功能。在主动脉位置,发现具有等效组织瓣环尺寸的 Lillehei-Kaster 和早期型号的 Starr-Edwards 假体在体内具有几乎相等的瓣膜面积。在大组织瓣环尺寸中,Lillehei-Kaster 二尖瓣提供的面积比 Starr-Edwards 假体更大。