Bedalov G, Vucković I, Fridrih S, Bruk M, Puskar D, Bartolin Z
Department of Urology, Zagreb General Hospital, Croatia.
Acta Med Croatica. 1994;48(3):105-9.
The paper deals with the incidence of prostatitis in benign prostatic hyperplasia (BPH) and its effect on the postoperative course in the patients subject to the transvesical prostatectomy. The samples of urine and expressed prostatic secretion were bacteriologically analysed before the operation, and samples of urine on three occasions following the operation. Specimens of BPH tissue obtained by surgery were subjected to pathohistological and microbiological examination. The incidence of prostatitis was found to be 90.3%. In the specimens of BPH tissue obtained by transversal prostatectomy, Gram-positive microorganisms were isolated in 32.8% of the tissue. In particular, Staphylococcus epidermidis was found in 26.6% of BPH tissue. Gram-negative microorganisms were isolated in 30.8% of BPH tissue, and fungi in 2.9%. In 27.9% of BPH tissue a microorganism could not be isolated although pathohistological examination evidenced prostatitis. Therefore, in these cases etiology remained unclear. Patients with Gram-negative prostatitis had the highest number of complications and the longest period of postoperative hospitalization. Preoperative and postoperative antibiotic therapy reduced the incidence of postoperative complications and shortened the period of hospitalization in the patients with significant Gram-negative bacteriuria before operation, that is, in the patients with Gram-negative prostatitis in BPH.
本文探讨良性前列腺增生（BPH）中前列腺炎的发生率及其对接受经膀胱前列腺切除术患者术后病程的影响。术前对尿液和前列腺按摩液样本进行细菌学分析，并在术后三个时间点采集尿液样本。对手术获取的BPH组织标本进行病理组织学和微生物学检查。发现前列腺炎的发生率为90.3%。在经横断前列腺切除术获取的BPH组织标本中，32.8%的组织分离出革兰氏阳性微生物。特别是，26.6%的BPH组织中发现表皮葡萄球菌。30.8%的BPH组织分离出革兰氏阴性微生物，2.9%分离出真菌。尽管病理组织学检查证实存在前列腺炎，但27.9%的BPH组织未分离出微生物。因此，在这些病例中病因仍不清楚。革兰氏阴性前列腺炎患者的并发症数量最多，术后住院时间最长。术前和术后抗生素治疗降低了术前有显著革兰氏阴性菌尿患者（即BPH合并革兰氏阴性前列腺炎患者）的术后并发症发生率，并缩短了住院时间。
