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经尿道球囊激光治疗(PROSTALASE)后犬前列腺的内镜及超声观察

Endoscopic and ultrasonographic observation of the canine prostate after transurethral balloon laser therapy (PROSTALASE).

作者信息

Kurokawa K, Suzuki T, Yamanaka H, Nakazato M, Daikuzono N, Long L M

机构信息

Department of Urology, Gunma University School of Medicine, Maebashi, Japan.

出版信息

J Endourol. 1994 Oct;8(5):379-84. doi: 10.1089/end.1994.8.379.

DOI:10.1089/end.1994.8.379
PMID:7532069
Abstract

We investigated the healing process and changes in the canine prostate after transurethral balloon-equipped laser (PROSTALASE) prostatectomy using both endoscopy and transrectal ultrasonography (TRUS). On TRUS, the prostate volume was significantly increased (123%) just after irradiation, decreasing to 106% at 1 week. Cavity formation was observed in the prostate 1 week after irradiation, and the median volume was 1.5 cm3 at 4 weeks. A TRUS study performed immediately after irradiation revealed a 1- to 2-mm deep hyperechoic lesion around the urethra. Urethrocystoscopy disclosed red and markedly edematous mucosa of the prostatic urethra, but no hemorrhage. The hyperechoic mass was also observed in the cavity on TRUS images 1 week later. Urethrocystoscopy disclosed abundant necrotic tissue within the cavity, and reddish granulomatous sections were observed on a portion of the cavity surface. At 4 weeks, the hyperechoic mass in the cavity was no longer observed on TRUS images. The prostate parenchyma was thin but uniformly isoechoic. At urethrocystoscopy, a smooth surface without redness and with the small craters, which were histologically identified as the duct openings of the prostate gland, were observed.

摘要

我们使用内窥镜检查和经直肠超声检查(TRUS),研究了配备球囊的经尿道激光(PROSTALASE)前列腺切除术后犬前列腺的愈合过程及变化。在TRUS检查中,照射后前列腺体积显著增大(123%),1周时降至106%。照射后1周在前列腺内观察到空洞形成,4周时中位体积为1.5 cm³。照射后立即进行的TRUS研究显示尿道周围有1至2毫米深的高回声病变。尿道膀胱镜检查发现前列腺尿道黏膜发红且明显水肿,但无出血。1周后在TRUS图像上的空洞内也观察到高回声肿块。尿道膀胱镜检查发现空洞内有大量坏死组织,在部分空洞表面观察到微红的肉芽肿样区域。4周时,TRUS图像上不再观察到空洞内的高回声肿块。前列腺实质变薄但回声均匀。在尿道膀胱镜检查中,观察到表面光滑、无发红,有小坑,组织学上确定为前列腺腺管开口。

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