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[老年隐匿性甲状腺功能亢进症的诊断失误]

[Diagnostic errors in symptom-poor hyperthyroidism in the aged].

作者信息

Szeszák F, Kiss E, Szabó T, Balázs C

机构信息

Hajdú-Bihar Megyei Onkormányzat Kenézy Gyula Kórház, III. Belgyógyászat, Debrecen.

出版信息

Orv Hetil. 1995 Feb 12;136(7):347-9.

PMID:7532848
Abstract

The diagnosis of hyperthyreoidism manifesting in the elderly meets difficulty in many cases. Lack of some characteristic symptoms observable in younger patients can be misleading. The authors summarize the data of ten clinical cases where the hyperthyreoidism appeared in occult form, reminding rather for heart disease or malignant tumours. The assay of thyroid hormones and the level of antithyreoglobulin and anti-thyreoid peroxidase antibodies was unavoidable in order to establish correct diagnosis. Though the early diagnosis and treatment may enhance the life expectancy of the patients and may considerably decrease the cardial and the consecutive cerebral complications. The authors analyse the reasons and possible pathomechanism of the formation of atypical hyperthyreoidism occurring in the elderly.

摘要

老年患者中出现的甲状腺功能亢进症在很多情况下诊断困难。缺乏年轻患者中可观察到的一些特征性症状可能会产生误导。作者总结了10例隐匿性甲状腺功能亢进症临床病例的数据,这些病例更容易被误诊为心脏病或恶性肿瘤。为了做出正确诊断,甲状腺激素测定以及抗甲状腺球蛋白和抗甲状腺过氧化物酶抗体水平检测必不可少。尽管早期诊断和治疗可能会提高患者的预期寿命,并可显著降低心脏及后续脑部并发症的发生率。作者分析了老年人非典型甲状腺功能亢进症形成的原因及可能的发病机制。

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