Flam F
Department of Gynecology and Obstetrics Karolinska Hospital, Stockholm, Sweden.
Eur J Gynaecol Oncol. 1994;15(6):443-8.
Twenty-five consecutive patients referred to the Department of Gynecology and Obstetrics, Karolinska Hospital, Stockholm, because of gestational trophoblastic neoplasia (GTN) had colour flow Doppler performed. The examinations were performed transabdominally in the initial ten patients and transvaginally thereafter. Tumour vessels within the uterus were detected in eighteen patients (72%). A negative colour Doppler finding in patients with persistent disease could imply a diagnosis of choriocarcinoma rather than invasive mole, but all five patients belonging to this group responded promptly to chemotherapy. There seems to be a rough correlation between extent of uterine disease, as judged by colour flow Doppler, and response to chemotherapy.
连续25例因妊娠滋养细胞肿瘤（GTN）转诊至斯德哥尔摩卡罗林斯卡医院妇产科的患者接受了彩色多普勒血流检查。最初10例患者经腹部进行检查，此后经阴道检查。18例患者（72%）在子宫内检测到肿瘤血管。持续性疾病患者彩色多普勒检查结果为阴性可能意味着诊断为绒毛膜癌而非侵蚀性葡萄胎，但该组5例患者对化疗均迅速起效。根据彩色多普勒血流判断，子宫疾病的程度与化疗反应之间似乎存在大致的相关性。
