Bargagna S
Istituto di Ricovero e Cura a Carattere Scientifico Stella Maris, Università degli Studi, Pisa.
Ann Ist Super Sanita. 1994;30(3):343-5.
Early diagnosis and treatment of congenital hypothyroidism (CH) changed the prognosis for affected subjects. However it is still matter of controversy whether the neuropsychological development of early treated CH children is completely normal. In our study, even if the cognitive development is within the normal range, several disturbances were repeatedly observed in the neurological area, in language and in behavioural aspects. Severe neonatal hypothyroidism and low socio-cultural level of the family were risk factors for these disturbances; our results emphasize the relevance of a neuropsychological follow-up of early treated CH children.
先天性甲状腺功能减退症(CH)的早期诊断和治疗改变了患病个体的预后。然而,早期接受治疗的CH儿童的神经心理发育是否完全正常仍是一个有争议的问题。在我们的研究中,即使认知发育在正常范围内,在神经学领域、语言和行为方面仍反复观察到一些障碍。严重的新生儿甲状腺功能减退症和家庭社会文化水平低是这些障碍的危险因素;我们的结果强调了对早期接受治疗的CH儿童进行神经心理随访的重要性。