Greinix H T, Beham-Schmid C, Silly H, Hoefler G, Kasparek A, Seewann H L
Department of Medicine I, University of Vienna, Austria.
Ann Hematol. 1995 Feb;70(2):109-12. doi: 10.1007/BF01834391.
A case of acute monocytic leukemia with rearrangement of the immunoglobulin heavy-chain gene and strong cytoplasmic immunoglobulin expression in a young patient treated with multi-drug chemotherapy for primary seminomatous germ cell tumor 13 months earlier is reported. The short latency period from the beginning of therapy for primary germ cell tumor and the abrupt onset of leukemia with no identifiable prodrome bear similarities to podophyllotoxin-related leukemias.
报告了一例急性单核细胞白血病病例，该患者为青年，13个月前因原发性精原细胞瘤接受多药化疗，存在免疫球蛋白重链基因重排且细胞质免疫球蛋白表达强烈。从原发性生殖细胞肿瘤治疗开始到白血病突然发作的潜伏期较短，且无明显前驱症状，这与鬼臼毒素相关白血病相似。
