Gupta S, Black D W, Smith D A
Creighton-Nebraska Department of Psychiatry at VAMC Omaha, Nebraska 68105.
Ann Clin Psychiatry. 1994 Sep;6(3):173-80. doi: 10.3109/10401239409149000.
The discovery of antipsychotic medications has revolutionized the treatment of schizophrenia and other psychotic disorders. However, side effects such as extrapyramidal symptoms (EPS) and tardive dyskinesia have been limiting factors in treatment. The introduction of atypical drugs such as clozapine and risperidone has ushered in a new era. This article provides an overview of the pharmacology, efficacy, and techniques for the clinical use of risperidone, which has recently become available.
抗精神病药物的发现彻底改变了精神分裂症和其他精神障碍的治疗方式。然而，锥体外系症状（EPS）和迟发性运动障碍等副作用一直是治疗中的限制因素。氯氮平和利培酮等非典型药物的引入开创了一个新时代。本文概述了最近可用的利培酮的药理学、疗效及临床应用技术。
