Devanne H, Gentil M, Maton B
Laboratoire de Physiologie du Mouvement, Université Paris-Sud, ERS CNRS 102, Orsay, France.
Electroencephalogr Clin Neurophysiol. 1995 Feb;97(1):29-35. doi: 10.1016/0924-980x(94)00269-d.
The jaw movement kinematics in relation to the EMG activity of two antagonistic jaw muscles (the masseter and the digastricus pars anterior) were examined in healthy subjects and patients with Friedreich's disease. Dysarthria and ataxia are the main characteristics of this disease. Jaw movement was monitored with a magnetometer system, and bipolar surface electrodes were used to record EMG activity. Unidirectional opening, unidirectional closing and opening-closing movements of the mandible were performed in a simple reaction time situation. The data were compared with those for normal control subjects. The kinematic and electromyographic characteristics were: (a) prolonged total movement duration resulting from increased acceleration and deceleration durations; (b) decreased maximum velocity, and a secondary peak in the velocity profile; (c) tonic EMG activity in muscles supposedly at rest; (d) prolonged EMG bursts. Premotor reaction time was also increased. These characteristics are similar to those, previously described, of limb movements in subjects with cerebellar dysfunctions and suggest that the alterations of jaw movement in Friedreich's ataxia could be due to a deficit in cerebellar control.
在健康受试者和弗里德赖希共济失调患者中，研究了与两块拮抗颌肌（咬肌和二腹肌前腹）肌电图活动相关的下颌运动学。构音障碍和共济失调是这种疾病的主要特征。使用磁力计系统监测下颌运动，并用双极表面电极记录肌电图活动。在简单反应时间情况下，进行下颌的单向开口、单向闭口和开口-闭口运动。将数据与正常对照受试者的数据进行比较。运动学和肌电图特征为：(a) 由于加速和减速持续时间增加导致总运动持续时间延长；(b) 最大速度降低，且速度曲线出现二次峰值；(c) 假定处于静止状态的肌肉出现紧张性肌电图活动；(d) 肌电图爆发延长。运动前反应时间也增加。这些特征与先前描述的小脑功能障碍受试者的肢体运动特征相似，表明弗里德赖希共济失调中下颌运动的改变可能是由于小脑控制缺陷所致。
