Göbel U B
Institut für Mikrobiologie und Hygiene, Universitätsklinikum Charité, Humboldt-Universität zu Berlin.
Verh Dtsch Ges Pathol. 1994;78:195-9.
With the advent of comparative rRNA sequence analysis and the introduction of molecular genetic methods, such as nucleic acid hybridization and amplification techniques, microbiology is gaining new grounds. Taxonomy based upon phylogenetic analysis leads to a reliable classification. Culture-independent identification procedures allow for the analysis of complex microbial ecosystems and the description of new, as-yet uncultivable infectious disease agents.
随着比较核糖体RNA序列分析的出现以及分子遗传学方法(如核酸杂交和扩增技术)的引入,微生物学正在开辟新领域。基于系统发育分析的分类学可实现可靠的分类。不依赖培养的鉴定程序有助于分析复杂的微生物生态系统,并描述新的、尚未培养的传染病病原体。