Fosså S D, Sokolowski J, Theodorsen L
Br J Urol. 1978 May;50(3):185-9. doi: 10.1111/j.1464-410x.1978.tb02800.x.
The levels of total and l-tartrate labile acid phosphatase were studied in 49 patients with prostatic carcinoma. The results were compared with the results from a control group. The acid phosphatase levels from the bone marrow were above the upper normal limit of serum acid phosphatase both in the control group and in patients with prostatic carcinoma. This may be due to acid phosphatase released from blood cells during haemolysis. There was a positive correlation between serum and bone marrow acid phosphatase levels in patients with prostatic carcinoma. Significantly raised levels of bone marrow acid phosphatase (above the upper limit of the normal range from the control group) were observed only in advanced stage IV patients with significantly increased serum levels. The levels of bone marrow acid phosphatase gave no supplementary diagnostic information in any of the patients with prostatic carcinoma. Doubt is expressed concerning the hypothesis that raised levels of bone marrow acid phosphatase are diagnostic of early metastases from prostatic carcinoma.
对49例前列腺癌患者的总酸性磷酸酶和L-酒石酸不稳定酸性磷酸酶水平进行了研究。将结果与对照组的结果进行了比较。对照组和前列腺癌患者骨髓中的酸性磷酸酶水平均高于血清酸性磷酸酶的正常上限。这可能是由于溶血过程中血细胞释放出酸性磷酸酶所致。前列腺癌患者血清和骨髓酸性磷酸酶水平之间存在正相关。仅在血清水平显著升高的晚期IV期患者中观察到骨髓酸性磷酸酶水平显著升高（高于对照组正常范围的上限）。骨髓酸性磷酸酶水平在任何前列腺癌患者中均未提供补充诊断信息。对于骨髓酸性磷酸酶水平升高可诊断前列腺癌早期转移这一假说表示怀疑。
