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瓣膜再次手术——风险因素的识别及与初次手术的比较

Valve reoperations--identification of risk factors and comparison with first-time operations.

作者信息

Christenson J T, Velebit V, Maurice J, Simonet F, Schmuziger M

机构信息

Cardiovascular Unit, Hôpital de la Tour, Meyrin-Geneva, Switzerland.

出版信息

Thorac Cardiovasc Surg. 1994 Dec;42(6):325-9. doi: 10.1055/s-2007-1016515.

DOI:10.1055/s-2007-1016515
PMID:7534950
Abstract

Fourty-seven patients with a least one heart valve operation each who underwent reoperations (Gr. I) were analyzed with special regard to risk factors influencing the perioperative mortality and compared to 203 patients operated for the first time (Gr. II) during the same time period. Mean age was 57.1 years in Gr. I and 64.1 years in Gr. II (p < 0.05). There were no differences between the groups with regard to sex, smoking, obesity, or concomitant peripheral vascular disease. Hypertension, hyperlipidemia, and diabetes were more frequently seen in Gr. I, p < 0.05. A significantly higher number of patients in the redo group (Gr. I) belonged preoperatively to NYHA class III or IV, p < 0.001 and needed emergency surgery more often, p < 0.01, but left-ventricular function did not differ between the groups. There was no significant difference in the position of valves operated or the number of multiple valve replacements/repairs between the groups, and no difference in aortic cross-clamping or cardiopulmonary bypass time. Most patients were referred from other hospitals. Overall perioperative mortality for Gr. I was 6.4% and Gr. II 4.4% (n.s.). Mortality after first reoperation was 5.0%, after second or more 14.3%. Perioperative mortality was related to age, preoperative NYHA class, and urgency of operation in both groups, and to multiple valve replacement/repair in Gr. I. Elective reoperation carried a mortality of 4.8% but emergency reoperation 20%; reoperation mortality was 2.6% for single valves and 25% for multiple valves.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

对47例至少接受过一次心脏瓣膜手术且接受再次手术的患者(第一组)进行分析,特别关注影响围手术期死亡率的危险因素,并与同期接受首次手术的203例患者(第二组)进行比较。第一组的平均年龄为57.1岁,第二组为64.1岁(p<0.05)。两组在性别、吸烟、肥胖或合并外周血管疾病方面无差异。高血压、高脂血症和糖尿病在第一组中更常见,p<0.05。再次手术组(第一组)术前属于纽约心脏协会(NYHA)III或IV级的患者数量显著更多,p<0.001,且更常需要急诊手术,p<0.01,但两组间左心室功能无差异。两组间手术瓣膜的位置或多瓣膜置换/修复的数量无显著差异,主动脉交叉阻断或体外循环时间也无差异。大多数患者是从其他医院转诊而来。第一组的总体围手术期死亡率为6.4%,第二组为4.4%(无统计学差异)。首次再次手术后的死亡率为5.0%,第二次或更多次手术后为14.3%。围手术期死亡率与两组患者的年龄、术前NYHA分级和手术紧迫性有关,在第一组中还与多瓣膜置换/修复有关。择期再次手术的死亡率为4.8%,但急诊再次手术为20%;单瓣膜再次手术的死亡率为2.6%,多瓣膜为25%。(摘要截断于250字)

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