Katircioğlu S F, Küçükaksu D S, Gökçe P, Ozgenci E, Tasdemir O, Bayazit K
Cardiovascular Surgery Clinic, Türkiye Yüksek Ihtisas Hospital, Ankara.
Thorac Cardiovasc Surg. 1994 Dec;42(6):330-2. doi: 10.1055/s-2007-1016516.
This study was planned to show the effect of retroperfusion and intraaortic balloon pumping (IABP) on myocardial hemodynamic recovery. Twelve dogs entered this study. Half of them received IABP and coronary sinus retroperfusion (CSPR) combination (Group II) and the remaining received IABP alone (Group I). Left anterior descending artery was occluded for a period of three hours. 15 minutes after occlusion IABP and IABP + CSRP were initiated. The average cardiac output was 1.41 +/- 0.18 L/min in the group I and 1.72 +/- 0.24 L/min in the group II (p < 0.03) after 3 hours of occlusion. Mean arterial pressure was 82.1 +/- 4.8 mmHg in the group I and 89.7 +/- 2.6 mmHg in the group II (p < 0.03). On the basis of this study it was concluded that CSRP + IABP could be an alternative treatment to IABP alone during the acutely developing ischemia.
本研究旨在显示逆行灌注和主动脉内球囊反搏（IABP）对心肌血流动力学恢复的影响。12只犬进入本研究。其中一半接受IABP与冠状窦逆行灌注（CSPR）联合治疗（第二组），其余仅接受IABP治疗（第一组）。左前降支动脉闭塞3小时。闭塞15分钟后开始IABP及IABP + CSRP治疗。闭塞3小时后，第一组平均心输出量为1.41±0.18 L/分钟，第二组为1.72±0.24 L/分钟（p<0.03）。第一组平均动脉压为82.1±4.8 mmHg，第二组为89.7±2.6 mmHg（p<0.03）。基于本研究得出结论，在急性缺血期，CSRP + IABP可作为单纯IABP的替代治疗方法。
