Maiorano E, Favia G
Institute of Pathological Anatomy, University of Bari.
Boll Soc Ital Biol Sper. 1994 Oct-Nov;70(10-11):287-94.
The parotidectomy specimens of 3 HIV-infected patients with lymphoepithelial cysts (CLL) have been used to study, with an immunohistochemical method, the expression of the following antigens in histopathological sections: Cytokeratins, CD3, CD20, CD35, CD68, MAC387, Kappa and Lambda light chains. The purpose of the study was to ascertain if CLL of salivary glands parallel the immunophenotype of extrasalivary systemic lymphadenopathy (LAS). The results of this study show that the epithelial lining of CLL does not derive from preexisting ducts and that the immunophenotype of CLL very closely resembles that of LAS. These features seem to suggest that CLL and LAS are tightly related diseases and that probably surgery is not the elective treatment for this lesion.
对3例患有淋巴上皮囊肿（CLL）的HIV感染患者的腮腺切除标本，采用免疫组织化学方法研究了组织病理学切片中以下抗原的表达：细胞角蛋白、CD3、CD20、CD35、CD68、MAC387、κ和λ轻链。本研究的目的是确定唾液腺CLL是否与唾液腺外系统性淋巴结病（LAS）的免疫表型相似。本研究结果表明，CLL的上皮衬里并非源自先前存在的导管，且CLL的免疫表型与LAS非常相似。这些特征似乎表明CLL和LAS是密切相关的疾病，并且手术可能并非该病变的首选治疗方法。
