Favia G, Capodiferro S, Scivetti M, Lacaita M G, Filosa A, Lo Muzio L
Department of Dental Sciences and Surgery, University of Bari, Bari, Italy.
Oral Dis. 2004 May;10(3):151-4. doi: 10.1046/j.1601-0825.2003.01006.x.
Bilateral and multiple lymphoepithelial cysts (LECs) of major salivary glands, in particular of parotid glands, are quite rare and have been reported in human immunodeficiency virus (HIV) infected patients with an incidence of about 3-6%. These lesions represent an early manifestation of HIV infection and are rarely found in patients with advanced acquired immunodeficiency syndrome.
Two cases of parotid LECs, the first occurring in a middle-age white woman and the second in a young white boy, both in advanced phases of HIV infection, are reported.
Clinical, cytological, histological and immunohistochemical (cytokeratin AE1/AE3, CD20, CD45RA, CD8, kappa and lambda immunoglobulin light chains, S-100, MLA and Ki67) features are described.
Fine needle aspiration (FNA), a relatively non-traumatic procedure, could represent both a diagnostic and a therapeutic tool in parotid LECs. No surgical therapy is usually required for these lesions and aspiration of cystic fluid with FNA is quite resolutive, although evidence of further relapses does exist. Surgical excision may become necessary when pain, because of persistent and progressive swelling of the parotid gland, occurs.
双侧及多发唾液腺淋巴上皮囊肿（LEC），尤其是腮腺的此类囊肿相当罕见，在人类免疫缺陷病毒（HIV）感染患者中报道的发病率约为3% - 6%。这些病变是HIV感染的早期表现，在晚期获得性免疫缺陷综合征患者中很少见。
报告了两例腮腺LEC病例，第一例发生在一名中年白人女性，第二例发生在一名年轻白人男孩，两人均处于HIV感染晚期。
描述了临床、细胞学、组织学和免疫组化（细胞角蛋白AE1/AE3、CD20、CD45RA、CD8、κ和λ免疫球蛋白轻链、S - 100、MLA和Ki67）特征。
细针穿刺抽吸（FNA）是一种相对无创的操作，可作为腮腺LEC的诊断和治疗工具。这些病变通常无需手术治疗，通过FNA抽吸囊液相当有效，尽管确实存在进一步复发的情况。当腮腺因持续渐进性肿胀而疼痛时，可能需要手术切除。
