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[进行性硬皮病患者体内的P物质和血管活性肠肽。自体训练前后血浆水平的测定]

[Substance P and vasoactive intestinal peptide in patients with progressive scleroderma. Determination of plasma level before and after autogenic training].

作者信息

Haustein U F, Weber B, Seikowski K

机构信息

Klinik und Poliklinik für Hautkrankheiten, Universität Leipzig.

出版信息

Hautarzt. 1995 Feb;46(2):102-6. doi: 10.1007/s001050050217.

DOI:10.1007/s001050050217
PMID:7535759
Abstract

In 12 patients suffering from systemic sclerosis (SSc) the influence of autogenic training on the plasma level of the neuropeptides substance P and vasoactive intestinal peptide (VIP) was studied. Compared with healthy controls the SSc patients exhibited significantly elevated levels of substance P (mean +/- SD: 7.1 +/- 3.2 pmol/l vs 1.6 +/- 1.6 pmol/l). Apart from variations the VIP plasma concentration did not significantly differ from that in healthy controls (mean +/- SD 10.7 +/- 7.1 pmol/l versus 12.0 +/- 5.3 pmol/l). Autogenic training did not bring about any significant changes in the plasma levels of neuropeptides.

摘要

对12例系统性硬化症(SSc)患者进行了自体训练对神经肽P物质和血管活性肠肽(VIP)血浆水平影响的研究。与健康对照组相比,SSc患者的P物质水平显著升高(平均值±标准差:7.1±3.2 pmol/l,而健康对照组为1.6±1.6 pmol/l)。除了有波动外,VIP血浆浓度与健康对照组相比无显著差异(平均值±标准差为10.7±7.1 pmol/l,健康对照组为12.0±5.3 pmol/l)。自体训练并未使神经肽的血浆水平发生任何显著变化。

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