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[成年和生长中大鼠的蛋白质饥饿以及消化和非消化器官酶系统和转运系统的营养屏障功能]

[Protein starvation and the trophic barrier functions of the enzymatic and transport systems of the digestive and nondigestive organs in adult and growing rats].

作者信息

Timofeeva N M, Iezuitova N N, Egorova V V, Nikitina A A, Gromova L V, Gordova L A

出版信息

Fiziol Zh Im I M Sechenova. 1994 Nov;80(11):91-103.

PMID:7536565
Abstract

A reduced activity of cytosol dipeptidases was revealed both in epithelial and subepithelial layers of the small intestine against the background of protein deprivation in adult and maturing rats. The latters' enzyme systems of the small intestine and kidneys' layers proved to be particularly sensitive to protein deprivation. The disturbance of the digestive-barrier functions provides favourable conditions for penetration of foreign protein and peptide substances into the organism's inner milieu which can be dangerous for a maturing organism.

摘要

在成年和正在成熟的大鼠蛋白质缺乏的背景下,小肠上皮和上皮下层的胞质二肽酶活性均降低。事实证明,小肠和肾层的酶系统对蛋白质缺乏尤为敏感。消化屏障功能的紊乱为外来蛋白质和肽类物质渗透到机体内部环境创造了有利条件,这对正在成熟的机体可能是危险的。

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