Bulas D I, Glass P, O'Donnell R M, Taylor G A, Short B L, Vezina G L
Department of Diagnostic Imaging and Radiology, Children's National Medical Center, Washington, DC 20010, USA.
Radiology. 1995 May;195(2):407-12. doi: 10.1148/radiology.195.2.7536947.
To determine if neuroimaging findings in infants who undergo extracorporeal membrane oxygenation (ECMO) are predictive of developmental outcome.
At 1-2 years of age, 183 ECMO survivors (69 female, 114 male) underwent developmental examination. Neuroimaging studies obtained at time of ECMO were assigned a neuroimaging score. Neuroimaging findings were correlated with developmental outcome.
Eighty-five infants had neuroimaging abnormalities. Development was normal in 105 infants, suspect in 37, and delayed in 41. Mean neuroimaging scores were significantly worse in survivors with delayed development (P < or = .0001). The sensitivity and specificity of normal neuroimaging findings in prediction of normal outcome were 65% and 63%, respectively. Survivors with nonhemorrhagic abnormalities had a higher risk of delayed development than did those with isolated hemorrhagic abnormalities (39% vs 21%).
Although they cannot be used alone to predict outcome, early neuroimaging scores can be used to assign risk categories for developmental outcome.
确定接受体外膜肺氧合（ECMO）治疗的婴儿的神经影像学检查结果是否可预测其发育结局。
183名ECMO治疗的幸存者（69名女性，114名男性）在1至2岁时接受了发育检查。在ECMO治疗时获得的神经影像学研究被赋予一个神经影像学评分。神经影像学检查结果与发育结局相关联。
85名婴儿存在神经影像学异常。105名婴儿发育正常，37名可疑，41名发育延迟。发育延迟的幸存者的平均神经影像学评分明显更差（P≤0.0001）。正常神经影像学检查结果预测正常结局的敏感性和特异性分别为65%和63%。非出血性异常的幸存者比孤立性出血性异常的幸存者发生发育延迟的风险更高（39%对21%）。
虽然早期神经影像学评分不能单独用于预测结局，但可用于为发育结局划分风险类别。
