恶性间皮瘤产生粒细胞集落刺激因子。

Production of granulocyte colony-stimulating factor by malignant mesothelioma.

作者信息

Rikimaru T, Ichikawa Y, Ogawa Y, Higuchi E, Kinosita M, Oizumi K, Shima I

机构信息

Dept of Medicine, University School of Medicine, Kurume, Japan.

出版信息

Eur Respir J. 1995 Jan;8(1):183-4. doi: 10.1183/09031936.95.08010183.

DOI:10.1183/09031936.95.08010183

PMID:7538085

Abstract

We present the case of a male patient, aged 45 yrs, with malignant mesothelioma producing granulocyte colony-stimulating factor (G-CSF). The diagnosis was established by histopathological examination of the autopsied pleural tissues. Production of G-CSF was confirmed by immunoperoxidase staining, using a specific monoclonal antibody against recombinant G-CSF (rhG-CSF).

摘要

我们报告一例45岁男性恶性间皮瘤患者，该肿瘤产生粒细胞集落刺激因子（G-CSF）。通过对尸检胸膜组织进行组织病理学检查确诊。使用抗重组G-CSF（rhG-CSF）的特异性单克隆抗体，通过免疫过氧化物酶染色证实了G-CSF的产生。