Law S F, Woulfe D, Reisine T
Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia 19104, USA.
Cell Signal. 1995 Jan;7(1):1-8. doi: 10.1016/0898-6568(94)00064-i.
Somatostatin (SRIF) induces its multiple biological actions by interacting with a family of receptors, referred to as SSTR1-SSTR5. These receptors are capable of associating with particular guanine nucleotide binding proteins to couple the receptors to distinct cellular effector systems. Therefore, G proteins have an important role in directing SRIF signalling and may provide the molecular basis for the diverse cellular actions of SRIF.
