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实验性甲状腺球蛋白免疫过程中抗体诱导的蛋白质和核酸代谢改变。

Antibody-induced alterations of protein and nucleic acid metabolism during experimental thyroglobulin immunization.

作者信息

Lahiri S, Chakraborty A

机构信息

Department of Animal Physiology, Bose Institute, Calcutta, India.

出版信息

Methods Find Exp Clin Pharmacol. 1994 Oct;16(8):563-7.

PMID:7539088
Abstract

The protein and nucleic acid contents of liver, spleen, muscle, kidney, and brain were studied in experimental autoimmune thyroiditis. Protein and ribonucleic acid levels showed a positive increase in the case of liver, spleen, and muscle on days 56 and 98 after immunization and on day 147 they reached control levels. Spleen deoxyribonucleic acid showed a significant increase on day 56, whereas the other days showed no change. Kidney and brain tissue revealed no change.

摘要

在实验性自身免疫性甲状腺炎中,对肝脏、脾脏、肌肉、肾脏和大脑的蛋白质和核酸含量进行了研究。在免疫后第56天和第98天,肝脏、脾脏和肌肉中的蛋白质和核糖核酸水平呈正向增加,在第147天达到对照水平。脾脏脱氧核糖核酸在第56天显著增加,而其他天数无变化。肾脏和脑组织无变化。

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