Honeycutt M E, Roberts B L, Roane D S
Department of Pharmacology/Toxicology, Northeast Louisiana University, Monroe 71209, USA.
Ecotoxicol Environ Saf. 1995 Mar;30(2):143-50. doi: 10.1006/eesa.1995.1018.
The disposition of cadmium was examined in the earthworm Eisenia fetida using two exposure media, filter paper, and artificial soil. Uptake and elimination rates were estimated to be 0.03039 and 0.00895 hr-1, respectively, for 1.25 micrograms Cd/cm2 filter paper exposure and 0.00512 and 0.00029 hr-1, respectively, for 10 micrograms Cd/g artificial soil exposure. The distribution of cadmium was examined using whole body autoradiography, tissue distribution, and subcellular localization. Cadmium tissue distribution was exposure-dependent, while cadmium subcellular localization apparently was not exposure-dependent. Acid-soluble thiol levels, examined as an index of cadmium exposure, were too variable in nonexposed earthworms to serve as an indicator of cadmium exposure.
利用两种暴露介质（滤纸和人工土壤）对赤子爱胜蚓体内镉的分布情况进行了研究。对于暴露于1.25微克镉/平方厘米滤纸的情况，摄取率和消除率分别估计为0.03039和0.00895小时-1；对于暴露于10微克镉/克人工土壤的情况，摄取率和消除率分别为0.00512和0.00029小时-1。使用全身放射自显影、组织分布和亚细胞定位对镉的分布进行了研究。镉的组织分布取决于暴露情况，而镉的亚细胞定位显然不取决于暴露情况。作为镉暴露指标进行检测的酸溶性硫醇水平，在未暴露的蚯蚓中变化太大，无法作为镉暴露的指标。
