Fungal metabolites. XVIII. New membrane-modifying peptides, trichorozins I-IV, from the fungus Trichoderma harzianum.
作者信息
Iida A, Sanekata M, Wada S, Fujita T, Tanaka H, Enoki A, Fuse G, Kanai M, Asami K
机构信息
Faculty of Pharmaceutical Sciences, Kyoto University, Japan.
出版信息
Chem Pharm Bull (Tokyo). 1995 Mar;43(3):392-7. doi: 10.1248/cpb.43.392.
PMID:7539721
Abstract
New membrane-modifying peptides, trichorozins I-IV, have been isolated from conidia of the fungus Trichoderma harzianum. Their amino acid sequences were clearly determined by spectrometric methods and, furthermore, they were synthesized by the solution-phase method. Trichorozins are a family of the class of peptaibols and are composed of 11 residues including an amino alcohol. Trichorozins exhibited voltage-dependent ion channel-like activity in lipid bilayers.
摘要
Zotero 插件