提取物的抗菌活性及其与抗葡萄球菌药物AFN-1252的协同作用。

Jankov Milica, Léguillier Vincent, Gašić Uroš, Anba-Mondoloni Jamila, Ristivojević Maja Krstić, Radoičić Aleksandra, Dimkić Ivica, Ristivojević Petar, Vidic Jasmina

Innovative Centre of the Faculty of Chemistry Ltd., Studentski trg 12-16, 11158 Belgrade, Serbia.

Micalis, AgroParisTech, National Research Institute for Agriculture, Food and the Environment (INRAE), University Paris-Saclay, UMR 1319, 78350 Jouy en Josas, France.

Foods. 2024 May 30;13(11):1715. doi: 10.3390/foods13111715.

, commonly known as the button mushroom, has attracted attention for its biological properties, including antimicrobial activities. Here, we evaluated the efficacy of ethanolic and acetonic extracts from white and brown against different bacterial strains, including antibiotic-resistant strains. Bioautography and principal component analysis identified the most active antibacterial compounds for each of the tested bacteria and indicated the main markers responsible for the strain-specific effects. In addition, the mushroom extracts demonstrated a synergistic impact when combined with the antistaphylococcal antibiotic AFN-1252.

通常被称为双孢蘑菇，因其生物学特性，包括抗菌活性而受到关注。在此，我们评估了白色和棕色双孢蘑菇乙醇提取物和丙酮提取物对不同细菌菌株，包括抗生素耐药菌株的功效。生物自显影和主成分分析确定了每种测试细菌中最具活性的抗菌化合物，并指出了造成菌株特异性效应的主要标志物。此外，蘑菇提取物与抗葡萄球菌抗生素AFN - 1252联合使用时显示出协同作用。