Allen A M, King R D
Lancet. 1978 Feb 18;1(8060):360-2. doi: 10.1016/s0140-6736(78)91084-x.
Occlusion of the skin renders it susceptible to acute fungal skin infections (dermatophytosis and candidiasis). Occlusion also raised carbon-dioxide (CO2) tensions at the skin's surface. Comparable CO2 tnesions have a pronounced effect on the morphology and metabolism of dermatophytes in vitro. It is postulated that dermatophyte conida and hyphae produce infective units under conditions of raised CO2 tensions, and that occlusion of the skin produces the concentrations of CO2 required for the conversion. Fungal skin infections might be prevented or controlled by interference with the action of CO2 or by prevention of its accumulation under wet, occlusive clothing.
皮肤闭塞会使其易患急性真菌性皮肤感染（皮肤癣菌病和念珠菌病）。闭塞还会提高皮肤表面的二氧化碳（CO₂）张力。在体外，类似的CO₂张力对皮肤癣菌的形态和代谢有显著影响。据推测，皮肤癣菌的分生孢子和菌丝在CO₂张力升高的条件下会产生感染单位，而皮肤闭塞会产生转化所需的CO₂浓度。通过干扰CO₂的作用或防止其在潮湿、闭塞的衣物下积聚，可以预防或控制真菌性皮肤感染。
