硫柳汞（一种巯基试剂）对子宫肌层节律性收缩的影响。
The effects of thimerosal, a sulfhydryl reagent, on phasic myometrial contractions.
作者信息
Phillippe M
机构信息
Department of Obstetrics & Gynecology, University of Chicago 60637, USA.
出版信息
Biochem Biophys Res Commun. 1995 Jun 6;211(1):1-6. doi: 10.1006/bbrc.1995.1769.
Thimerosal inhibits calcium uptake and IP3-induced calcium release from IP3-sensitive endoplasmic reticulum; this study sought to evaluate the effects of thimerosal on agonist-stimulated phasic myometrial contractions. Thimerosal was found to significantly inhibit phasic contractions stimulated by oxytocin, aluminum fluoride, potassium chloride, ionomycin, and Bay K 8644. These observations provide support for the hypothesis that calcium uptake and IP3-induced calcium release are important events during agonist-stimulated phasic myometrial contractions.
硫柳汞抑制钙摄取以及由肌醇三磷酸（IP3）敏感的内质网释放IP3诱导的钙；本研究旨在评估硫柳汞对激动剂刺激的子宫肌层相性收缩的影响。结果发现硫柳汞能显著抑制由催产素、氟化铝、氯化钾、离子霉素和Bay K 8644刺激引起的相性收缩。这些观察结果支持了以下假说，即钙摄取和IP3诱导的钙释放是激动剂刺激子宫肌层相性收缩过程中的重要事件。
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