转移性肾上腺皮质癌的分泌症状对奥曲肽有反应。
Secretory symptoms from metastatic adrenal cortical carcinoma responding to octreotide.
作者信息
Pandha H S, Harrington K, Saini S, Lynn J, Peters M, Waxman J
机构信息
Department of Clinical Oncology, Hammersmith Hospital, London, UK.
出版信息
Postgrad Med J. 1995 Apr;71(834):229-30. doi: 10.1136/pgmj.71.834.229.
Abstract
The prognosis of patients with metastatic adrenal cortical carcinoma is poor, and their disabling symptoms are usually unresponsive to conventional therapy. A patient with Cushing's syndrome secondary to a secretory adrenal cortical carcinoma was treated with octreotide, endocrine therapy and chemotherapy having failed. Treatment led to a dramatic relief of her symptoms with a fall in corticosteroid secretion. Somatostatin analogue therapy for this tumour should be encouraged in view of the lack of alternative palliative treatment.
摘要
转移性肾上腺皮质癌患者的预后较差，其致残症状通常对传统治疗无反应。一名继发于分泌性肾上腺皮质癌的库欣综合征患者，在奥曲肽治疗前，内分泌治疗和化疗均失败。治疗使她的症状得到显著缓解，皮质类固醇分泌下降。鉴于缺乏其他姑息治疗方法，应鼓励对该肿瘤采用生长抑素类似物治疗。
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