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冠状动脉血管成形术失败后行冠状动脉旁路移植术:危险因素及长期结果

Coronary artery bypass grafting after failed coronary angioplasty: risk factors and long-term results.

作者信息

Nollert G, Amend J, Detter C, Reichart B

机构信息

Department of Cardiac Surgery, University Clinic of Grosshadern, Ludwig-Maximilians University, Munich, Germany.

出版信息

Thorac Cardiovasc Surg. 1995 Feb;43(1):35-9. doi: 10.1055/s-2007-1013765.

Abstract

In this case-control study we investigated the preoperative risk factors and long-term results in patients undergoing emergency coronary artery bypass grafting (CABG) after failed percutaneous transluminal coronary angioplasty (PTCA). From January 1990 to March 1993, 56 emergency CABGs (Group A) were performed in patients from 7 different cardiology centres--six of these located outside our hospital within a radius of 19 km-1 h to 114 h (phi 7.3 h) after failed PTCA. No special stand-by was given and patients were operated in the next available theatre. Criteria of anatomically unfavourable stenoses for PTCA were defined as follows: Long stenoses, occlusions of other major vessels, tandem stenoses, stenoses at or near a bend or branch and, finally, eccentric stenoses. Thirty-two percent met one criterion, 35.8% two, 6.9% three and 1.8% four criteria. All patients were examined echocardiographically 14.6 +/- 8.2 months postoperatively. Patients who had been operated on electively within the same period served as a control (Group B; n = 56; case-control study). The patients were matched for age, sex, EF, LVEDP, body surface area, reoperation status, and concomitant diseases. The mortality rate for Group A patients was 10.7% (n = 6); for Group B, 1.8% (n = 1). Five of the Group A patients who died came from our own hospital and only one from a hospital 1 km away (mortality: 14.3% vs. 4.8%). There were no deaths among patients with an anatomically favourable stenosis for a PTCA; in patients with more than one criterion for an unfavourable stenosis mortality increased to 19.0% (p < 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

在这项病例对照研究中,我们调查了经皮腔内冠状动脉成形术(PTCA)失败后接受急诊冠状动脉旁路移植术(CABG)患者的术前危险因素和长期结果。1990年1月至1993年3月,7个不同心脏病中心的患者接受了56例急诊CABG(A组)——其中6个位于我院外半径19公里处,PTCA失败后1小时至114小时(平均7.3小时)。未做特殊准备,患者在有空的手术室接受手术。PTCA解剖学上不利狭窄的标准定义如下:长狭窄、其他主要血管闭塞、串联狭窄、弯曲或分支处或附近的狭窄以及最后偏心狭窄。32%符合一项标准,35.8%符合两项,6.9%符合三项,1.8%符合四项标准。所有患者术后14.6±8.2个月接受超声心动图检查。同期接受择期手术的患者作为对照(B组;n = 56;病例对照研究)。患者在年龄、性别、射血分数、左心室舒张末压、体表面积、再次手术状态和伴发疾病方面进行匹配。A组患者死亡率为10.7%(n = 6);B组为1.8%(n = 1)。A组死亡的6例患者中有5例来自我院,仅1例来自1公里外的医院(死亡率:14.3%对4.8%)。PTCA解剖学上有利狭窄的患者无死亡;解剖学上不利狭窄标准超过一项的患者死亡率增至19.0%(p<0.05)。(摘要截短于250字)

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