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[PTCA失败后急诊冠状动脉血运重建的个人经验——早期和晚期结果]

[Personal experiences with emergency coronary artery revascularization after failed PTCA--early and late results].

作者信息

Simic O, Maring J, Stein J, Meinertz T, Ostermeyer J

机构信息

Abteilung für Herzchirurgie, Allgemeines Krankenhaus St. Georg, Hamburg.

出版信息

Zentralbl Chir. 1997;122(3):149-52.

PMID:9206907
Abstract

In recent years the equipment and techniques for percutaneous transluminal coronary angioplasty (PTCA) have been improved and today complex and distal stenoses are also treated in this way. Subsequent to failed PTCA some patients undergo emergency CABG. Between January 1991 and March 1995 3,520 patients have been treated by PTCA in our hospital. 61 patients (1.7%), mean age 61.1 years, underwent subsequent emergency CABG after PTCA. 46% had single-, 33% double and 21% had triple-vessel-disease, the mean left ventricular function (LVEF) was 65%. The mean number of bypass grafts was 1.9. The internal mammary arteries were never used under these emergency conditions. 9 patients (15%) developed perioperative myocardial infarction and in two of them the LVEF decreased under 30%. The hospital mortality was 6.6% (= 4 perioperative deaths). 6 of 61 patients were lost for follow-up; 90% of the hospitals survivors were followed for 244 months (mean 17). During this period there were 4 late deaths (3 cardiac and 1 non-cardiac). Actuarial survival at one year was 90%. 80% of the long-term survivors were in the NYHA functional classes I and II. In patients with double- or triple-vessel-disease PTCA almost always effects an incomplete revascularisation. Emergency CABG following failed PTCA is associated with an increased mortality and morbidity. The long-term prognosis is similar to that of an age-sex matched general population.

摘要

近年来,经皮腔内冠状动脉成形术(PTCA)的设备和技术不断改进,如今复杂和远端狭窄也采用这种方法治疗。PTCA失败后,一些患者接受急诊冠状动脉搭桥术(CABG)。1991年1月至1995年3月,我院共有3520例患者接受了PTCA治疗。61例患者(1.7%),平均年龄61.1岁,在PTCA后接受了急诊CABG。46%为单支血管病变,33%为双支血管病变,21%为三支血管病变,平均左心室功能(LVEF)为65%。平均搭桥血管数为1.9支。在这些急诊情况下从未使用过乳内动脉。9例患者(15%)发生围手术期心肌梗死,其中2例LVEF降至30%以下。医院死亡率为6.6%(=4例围手术期死亡)。61例患者中有6例失访;90%的医院幸存者接受了244个月(平均17个月)的随访。在此期间有4例晚期死亡(3例心脏原因和1例非心脏原因)。1年的精算生存率为90%。80%的长期幸存者属于纽约心脏协会(NYHA)心功能I级和II级。在双支或三支血管病变的患者中,PTCA几乎总是导致不完全血运重建。PTCA失败后急诊CABG与死亡率和发病率增加相关。长期预后与年龄和性别匹配的普通人群相似。

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