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恶性食管狭窄与瘘:用聚氨酯覆膜的朱尔科支架进行姑息治疗

Malignant esophageal stricture and fistula: palliative treatment with polyurethane-covered Gianturco stent.

作者信息

Miyayama S, Matsui O, Kadoya M, Yoshikawa J, Gabata T, Kitagawa K, Arai K, Takashima T

机构信息

Department of Radiology, Kanazawa University School of Medicine, Japan.

出版信息

J Vasc Interv Radiol. 1995 Mar-Apr;6(2):243-8. doi: 10.1016/s1051-0443(95)71105-8.

Abstract

PURPOSE

To evaluate the effectiveness of a polyurethane-covered Gianturco stent in the palliative treatment of malignant esophageal stricture and fistula.

PATIENTS AND METHODS

Twenty-seven patients with recurrent stricture (n = 24), fistula formation (n = 8), or both (n = 5) underwent palliative treatment for aphagia (n = 15) or dysphagia (n = 12). Eight patients had fistulas to the respiratory tract or mediastinum. A 15-F delivery sheath system was passed through the stricture; the inner dilator was removed, and the stent was compressed into the sheath and advanced with a pusher catheter. Follow-up included chest radiography for 3 days and monthly esophagography or endoscopy.

RESULTS

Covered stents occluded fistulas and opened strictures in 100% of patients. Food intake was upgraded to liquids in 7% of patients, to soft foods in 37% and to regular foods in 56%. New stricture or fistula occurred in 4% and 7% of patients, respectively. Stent migration occurred in 15% of patients. Twenty-one patients died after stent placement, and average life expectancy was 11 weeks.

CONCLUSION

A polyurethane-covered Gianturco stent is effective in the palliation of advanced malignant esophageal strictures and fistulas.

摘要

目的

评估聚氨酯覆膜Gianturco支架在恶性食管狭窄和瘘的姑息治疗中的有效性。

患者与方法

27例复发性狭窄(n = 24)、瘘形成(n = 8)或两者兼具(n = 5)的患者接受了吞咽困难(n = 15)或吞咽障碍(n = 12)的姑息治疗。8例患者出现呼吸道或纵隔瘘。通过狭窄处置入一个15F输送鞘系统;取出内扩张器,将支架压缩入鞘内,并用推送导管推进。随访包括3天的胸部X线检查以及每月的食管造影或内镜检查。

结果

覆膜支架使100%的患者瘘口闭塞、狭窄开通。7%的患者食物摄入改善至流食,37%改善至软食,56%改善至正常饮食。新的狭窄或瘘分别出现在4%和7%的患者中。15%的患者发生支架移位。21例患者在支架置入后死亡,平均预期寿命为11周。

结论

聚氨酯覆膜Gianturco支架在晚期恶性食管狭窄和瘘的姑息治疗中有效。

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