Duvelleroy-Hommet C, Billard C, Lucas B, Gillet P, Barthez M A, Santini J J, Degiovanni E, Henry F, De Toffol B, Autret A
Service de Neurochirurgie-Neurologie Pédiatriques, Hôpital de Clocheville, France.
Neuropediatrics. 1995 Feb;26(1):14-8. doi: 10.1055/s-2007-979713.
In order to clarify the relationship between developmental dysphasia and EEG abnormalities, paroxysmal activities during sleep were studied in a series of 24 children with expressive developmental dysphasia (mean age 8 years) and compared to a control group of 39 children (mean age 9 years). The children of both groups were selected excluding cases with prior history of neurological disease or epilepsy. In the control group, 37 children had normal sleep EEG while 2 children had paroxysmal abnormalities. In the dysphasic group, epileptic abnormalities were observed in 9 cases, rare in 4 cases and frequent in 5 cases (density: 2.5 to 66.2% of total sleep time). Nevertheless, paroxysmal abnormalities did not reach the frequency described in the Landau-Kleffner syndrome, and it is unlikely that EEG abnormalities could have produced dysphasia.
为了阐明发育性语言障碍与脑电图异常之间的关系，对一系列24名表达性发育性语言障碍儿童（平均年龄8岁）睡眠期间的阵发性活动进行了研究，并与39名儿童（平均年龄9岁）的对照组进行了比较。两组儿童均排除有神经疾病或癫痫病史的病例。在对照组中，37名儿童睡眠脑电图正常，2名儿童有阵发性异常。在语言障碍组中，9例观察到癫痫样异常，4例少见，5例频繁（密度：占总睡眠时间的2.5%至66.2%）。然而，阵发性异常未达到Landau-Kleffner综合征中描述的频率，脑电图异常不太可能导致语言障碍。
