针对IgE的自身抗体在IgE介导的反应中起作用吗？
Do autoantibodies to IgE play a role in IgE-mediated events?
作者信息
Shakib F, Smith S J, Pritchard D I
机构信息
Department of Immunology, Medical School, Queen's Medical Centre, Nottingham, UK.
出版信息
Immunol Cell Biol. 1995 Apr;73(2):109-12. doi: 10.1038/icb.1995.18.
PMID:7541018
Abstract
Elevated blood levels of IgG anti-IgE are detectable in individuals exhibiting enhanced IgE production, namely those with allergic conditions and helminthic parasite infections. The fact that there are epitope-specific subpopulations of autoanti-IgE suggests that this autoantibody could potentially have multiple effects in immunological events involving IgE.
摘要
在表现出IgE产生增强的个体中，即患有过敏性疾病和蠕虫寄生虫感染的个体中，可检测到血液中IgG抗IgE水平升高。自身抗IgE存在表位特异性亚群这一事实表明，这种自身抗体可能在涉及IgE的免疫事件中具有多种作用。
Zotero 插件