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一例晚期真性红细胞增多症患者脾脏照射后肝髓外化生的抑制(作者译)

[Suppression of hepatic myeloid metaplasia after irradiation of the spleen in a case of spent polycythemia (author's transl)].

作者信息

Charbord P, Gardet P, Caillou B, Parmentier C

出版信息

Nouv Rev Fr Hematol (1978). 1978 Nov 25;20(3):435-42.

PMID:754174
Abstract

In a case of spent polycythemia after irradiation of the spleen alone (450 rad in 17 sessions and 28 days) the suppression of any hepatic myeloid metaplasia was observed simultaneously with the regression of myelemia and erythroblastemia and the drop in the number of circulating granulomonocytic stem cells. These observations allow to discuss the mode of action of the splenic radiotherapy and the relationship between myeloid metaplasia and the circulating hematopoietic cells (proliferating granulocytic and erythrocytic cells and stem cells).

摘要

在仅对脾脏进行照射(17次,共450拉德,照射时间为28天)后出现消耗性红细胞增多症的病例中,观察到在骨髓性贫血和成红细胞血症消退以及循环粒细胞单核细胞干细胞数量下降的同时,任何肝髓外化生均受到抑制。这些观察结果有助于探讨脾放疗的作用方式以及髓外化生与循环造血细胞(增殖性粒细胞和红细胞以及干细胞)之间的关系。

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