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肠炎沙门氏菌中O抗原生物合成的转移酶:B组和C2组的双脱氧己糖基转移酶以及C2组的乙酰转移酶。

Transferases of O-antigen biosynthesis in Salmonella enterica: dideoxyhexosyltransferases of groups B and C2 and acetyltransferase of group C2.

作者信息

Liu D, Lindqvist L, Reeves P R

机构信息

Department of Microbiology, University of Sydney, New South Wales, Australia.

出版信息

J Bacteriol. 1995 Jul;177(14):4084-8. doi: 10.1128/jb.177.14.4084-4088.1995.

Abstract

The O antigen is a polymer of oligosaccharide units. O antigens differ in their sugar composition and glycosidic linkages, and genes responsible for O-antigen-specific biosynthesis are grouped in the rfb gene cluster. In this study, we identified two abequosyltransferase genes and an acetyltransferase gene in Salmonella enterica groups B and C2 by in vitro assay and identified paratosyl-, tyvelosyl-, and abequosyltransferase genes from S. enterica groups A and D and Yersinia pseudotuberculosis serovar IIA, respectively, by comparison.

摘要

O抗原是寡糖单元的聚合物。O抗原在其糖组成和糖苷键方面存在差异,负责O抗原特异性生物合成的基因聚集在rfb基因簇中。在本研究中,我们通过体外试验在肠炎沙门氏菌B群和C2群中鉴定出两个阿比可糖基转移酶基因和一个乙酰转移酶基因,并通过比较分别从肠炎沙门氏菌A群和D群以及假结核耶尔森氏菌血清型IIA中鉴定出对甲苯磺酰基、泰威糖基和阿比可糖基转移酶基因。

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