DuBeau C E, Sullivan M P, Cravalho E, Resnick N M, Yalla S V
Urology Division, Brockton/West Roxbury Veterans Administration Medical Center, Boston, Massachusetts, USA.
J Urol. 1995 Aug;154(2 Pt 1):498-503. doi: 10.1097/00005392-199508000-00044.
We correlate micturitional urethral pressure profilometry with pressure-flow diagnoses of outlet obstruction.
Urodynamic evaluation was done of 86 consecutive men with voiding symptoms. Obstruction criteria were a micturitional urethral pressure profile (MUPP) gradient greater than 5 cm. water, Schäfer's linear passive urethral resistance relation (PURR) greater than grade 1 and Abrams-Griffiths nomogram.
Interpretable results were completed in 99% of the patients undergoing MUPP and 60% undergoing pressure-flow studies (p < 0.00001). MUPP diagnosis agreed with PURR (p = 0.0015) and Abrams-Griffiths nomogram results (p = 0.00004). MUPP gradients correlated well with PURR (r = 0.70, p < 0.00001). Using optimum cutoff values (11 cm. water), the sensitivity of MUPP was 83%, specificity 82% and positive predictive value 94%.
MUPP correlates well with and yields interpretable results more often than pressure-flow studies.
我们将排尿期尿道压力测定与出口梗阻的压力-流率诊断相关联。
对86例有排尿症状的男性进行了尿动力学评估。梗阻标准为排尿期尿道压力曲线（MUPP）梯度大于5厘米水柱、施费尔线性被动尿道阻力关系（PURR）大于1级以及艾布拉姆斯-格里菲思列线图。
99%接受MUPP检查的患者和60%接受压力-流率研究的患者获得了可解释的结果（p < 0.00001）。MUPP诊断与PURR（p = 0.0015）和艾布拉姆斯-格里菲思列线图结果（p = 0.00004）一致。MUPP梯度与PURR相关性良好（r = 0.70，p < 0.00001）。使用最佳临界值（11厘米水柱）时，MUPP的敏感性为83%，特异性为82%，阳性预测值为94%。
与压力-流率研究相比，MUPP相关性良好且更常产生可解释的结果。
