Porzsolt F, Zeeh J, Platt D
Department of Medicine III, University of Ulm, Germany.
Drugs Aging. 1995 Mar;6(3):192-209. doi: 10.2165/00002512-199506030-00003.
Palliative therapy in elderly cancer patients deserves special attention because of differences between young and elderly cancer patients. In elderly patients, the treatment produces more adverse effects and the disease is cured less frequently, but the prognosis is usually better than in young patients with cancer. In the elderly population, cancer is seen more frequently than in the young population, yet elderly patients are less frequently included in trials. It is obvious that the results obtained from the treatment of young cancer patients do not necessarily apply to elderly cancer patients. The existing lack of formal data for the management of elderly cancer patients justifies 5 distinctive steps: collection of individual information; review of the available and appropriate knowledge; definition and specification of treatment goals; selection of treatment tools; and assessment of outcome. Following these steps will lead to coordination of oncology and palliative medicine.
由于老年癌症患者与年轻癌症患者存在差异,老年癌症患者的姑息治疗值得特别关注。在老年患者中,治疗产生的不良反应更多,疾病治愈的频率更低,但预后通常比年轻癌症患者更好。在老年人群中,癌症的发病率比年轻人群更高,但老年患者较少被纳入试验。显然,从年轻癌症患者治疗中获得的结果不一定适用于老年癌症患者。目前缺乏针对老年癌症患者管理的正式数据,这证明了五个独特步骤的合理性:收集个人信息;回顾可用的适当知识;定义和明确治疗目标;选择治疗工具;以及评估结果。遵循这些步骤将实现肿瘤学和姑息医学的协调。