Ravina J H, Herbreteau D, Ciraru-Vigneron N, Bouret J M, Houdart E, Aymard A, Merland J J
Service de Gynécologie Obstétrique, Hôpital Lariboisière, Université Paris VII, France.
Lancet. 1995 Sep 9;346(8976):671-2. doi: 10.1016/s0140-6736(95)92282-2.
Haemorrhage, probably related to hypervascularisation, is the commonest complication of uterine myomata and is difficult to treat. 16 patients, aged 34-48 years, with symptomatic uterine myomata, for which a major surgical procedure was planned after failure of medical treatment, were treated by selective free-flow arterial embolisation of the myomata with Ivalon particles. With a mean follow-up of 20 months (range 11-48) in the responders, symptoms resolved in 11 patients; menstrual cycles returned to normal in ten of these. Three patients had partial improvement. Two failures required surgery. In 14 cases embolisation caused pelvic pain, which required analgesia in all.
出血可能与血管过度增生有关,是子宫肌瘤最常见的并发症且难以治疗。16例年龄在34 - 48岁、有症状性子宫肌瘤且药物治疗失败后计划进行大型外科手术的患者,接受了用Ivalon颗粒对肌瘤进行选择性自由流动动脉栓塞治疗。在有反应的患者中,平均随访20个月(范围11 - 48个月),11例患者症状消失;其中10例患者月经周期恢复正常。3例患者有部分改善。2例治疗失败需要进行手术。14例患者栓塞后出现盆腔疼痛,均需要镇痛治疗。