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野生哺乳动物蠕虫病的化学疗法。IV. 5%氟苯达唑(R17889)对阿拉伯狒狒(Papio hamadryas L.)毛首鞭形线虫感染的疗效

Chemotherapy of helminthiasis among wild mammals. IV. Efficacy of flubendazole 5% (R17889) against Trichuris trichiura infection of baboons, Papio hamadryas L.

作者信息

Kumar V, Ceulemans F, De Meurichy W

出版信息

Acta Zool Pathol Antverp. 1978 Nov(73):3-9.

PMID:754549
Abstract

Flubendazole 5%, a parafluor analog of benzimidazole derivative, mebendazole, was found efficient in eliminating Trichuris trichiura infection of baboons when administered orally at a dose rate of 27 to 50 mg of the active ingredient per kg body weight twice daily for five days. The drug was found safe, without toxic effects and its palatability was excellent.

摘要

5%氟苯达唑是苯并咪唑衍生物甲苯达唑的对氟类似物,当以每千克体重27至50毫克活性成分的剂量口服给药,每日两次,持续五天时,发现其对消除狒狒的毛首鞭形线虫感染有效。该药物被发现是安全的,没有毒性作用,并且适口性极佳。

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